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How else are you going to separate distinct cell type populations for proteomics? This isn't, nonetheless what this group is focusing on! They are using chemical labeling methods that can allow them to either bodily separate the cells OR to only be able to inform afterward from the proteomics or transcriptomics the place that particular cell came from! This paper is OPEN, so I'm gonna borrow a part of a desk to point out you why it is best to test this out! That is the center piece of this awesome paper. The strategy -- what you possibly can study -- a quick overview -- the two "Sure" is whether or not it is suitable with secreted proteins then whether or not it's appropriate with PTMs. They then go into advantages/disadvantages of the strategies! Each of these technique bears further investigation! Oh -- as a result of generally you simply cannot separate the individual cells. It can be staggering. Simply the data discount alone at the tip -- not to mention -- the opportunity of utilizing the instrument to only concentrate on the tagged proteins -- but I'm getting simply a bit of forward of myself.
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